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Title: False-positive galactomannan platelia Aspergillus test results for patients receiving piperacillin-tazobactam
Authors: Viscoli, Claudio
Machetti, Marco
Cappellano, Paola [UNIFESP]
Bucci, Barbara
Bruzzi, Paolo
Van Lint, Maria Teresa
Bacigalupo, Andrea
Natl Inst Canc Res
Univ Genoa
Osped San Martino Genova
Universidade Federal de São Paulo (UNIFESP)
Issue Date: 15-Mar-2004
Publisher: Univ Chicago Press
Citation: Clinical Infectious Diseases. Chicago: Univ Chicago Press, v. 38, n. 6, p. 913-916, 2004.
Abstract: At the bone marrow transplantation center of the San Martino Hospital ( Genoa), we observed an increase in the rate of patients with positive Platelia Aspergillus (PA; Bio-Rad) test results, from 10% ( 38 of 386 patients) in the period from January 1999 through January 2003 to 36% ( 21 of 59 patients) in the period from February 2003 through May 2003. Positivity was significantly (P < .001) associated with the administration of piperacillin-tazobactam (PT) (17 [74%] of 23 patients who received PT had positive results vs. 4 [11%] of 36 who did not receive PT). Multivariate analysis found administration of PT (&chi;2 = 34.7; P < .001) and underlying disease (chi(2) = 21.14; P < .001) to be associated with PA positivity. of 15 PT batches tested, 12 had positive PA test results.
ISSN: 1058-4838
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