IgE antibody responses in young children with atopic dermatitis

IgE antibody responses in young children with atopic dermatitis

Autor Wahn, U. Google Scholar
Warner, J. Google Scholar
Simons, F. E. R. Google Scholar
Benedictis, F. M. de Google Scholar
Diepgen, T. L. Google Scholar
Naspitz, C. K. Autor UNIFESP Google Scholar
Longueville, M. de Google Scholar
Bauchau, V. Google Scholar
EPAAC Study Grp Google Scholar
Instituição Univ London Imperial Coll Sci Technol & Med
Childrens Hosp
Salesi Childrens Hosp
Univ Heidelberg Hosp
Universidade Federal de São Paulo (UNIFESP)
UCB
Univ Kinder & Poliklin Klin Padiatrie Schwerpunkt
Resumo In 2184 young children aged 13-24 months with atopic dermatitis (SCORAD 5-59) serum IgE antibodies to a standard panel of food and inhalant allergens were assayed. the frequency of positive IgE responses (> 0.35 kU/l) increased with greater severity of skin disease. A significant minority of infants had levels of IgE antibody to foods to suggest they were at risk of acute reaction to those foods (7% to hen's egg, 3% to cow's milk, 4% to peanut). Our findings indicate that the frequency of positive IgE responses is related to disease severity and suggest that differences in the time course of the development of IgE responses to food, which are at maximum prevalence within the first year of life, while inhalant allergies, are still developing between 1 and 2 yr and beyond.
Assunto atopic dermatitis
IgE
sensitization
child
Idioma Inglês
Data 2008-06-01
Publicado em Pediatric Allergy and Immunology. Malden: Wiley-Blackwell, v. 19, n. 4, p. 332-336, 2008.
ISSN 0905-6157 (Sherpa/Romeo, fator de impacto)
Editor Wiley-Blackwell
Extensão 332-336
Fonte http://dx.doi.org/10.1111/j.1399-3038.2007.00643.x
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000255835900008
URI http://repositorio.unifesp.br/handle/11600/30720

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