The impact of tonic immobility reaction on the prognosis of posttraumatic stress disorder

The impact of tonic immobility reaction on the prognosis of posttraumatic stress disorder

Autor Lima, Alessandra A. Google Scholar
Fiszman, Adriana Google Scholar
Marques-Portella, Carla Google Scholar
Mendlowicz, Mauro V. Google Scholar
Coutinho, Evandro S. F. Google Scholar
Maia, Deborah C. B. Google Scholar
Berger, William Google Scholar
Rocha-Rego, Vanessa Google Scholar
Volchan, Eliane Google Scholar
Mari, Jair J. Autor UNIFESP Google Scholar
Figueira, Ivan Google Scholar
Instituição Universidade Federal do Rio de Janeiro (UFRJ)
Universidade Federal Fluminense (UFF)
ENSP
Universidade Federal de São Paulo (UNIFESP)
Resumo Tonic immobility is the last defense reaction to entrapment by a predator. in humans, peritraumatic tonic immobility was correlated with PTSD severity and poor response to treatment. This study compared the role of peritraumatic dissociation, panic physical symptoms and tonic immobility as predictors of response to standard pharmacotherapy for PTSD. Thirty-six PTSD patients underwent a naturalistic pharmacological treatment. the Posttraumatic Stress Disorder Checklist - Civilian Version (PCL-C) and the Clinical Global Impressions Severity of Illness item scores (CGI-S) were employed at baseline and endpoint to examine treatment outcome. Peritraumatic reactions were assessed using the Physical Reactions Subscale, the Peritraumatic Dissociative Experiences Questionnaire and four motor questions of the Tonic Immobility Scale. After controlling for confounders, tonic immobility was the best predictor of a poor response to treatment, either considering the PCL-C or the CGI-S scores. Tonic immobility seems to have a greater negative impact on PTSD prognosis than peritraumatic panic or dissociation. Additional translational and clinical research may inform about particular mechanisms underlying tonic immobility and open new avenues for prevention and treatment of PTSD. (C) 2009 Elsevier B.V. All rights reserved.
Assunto PTSD
Peritraumatic reactions
Tonic immobility
Dissociation
Panic
Prognosis
Drug therapy
Idioma Inglês
Financiador Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
IBN Net/FINEP
Millennium Institute
Confederacao Nacional do Comercio
Número do financiamento Millennium Institute: 420122
Millennium Institute: 2005-2
Data 2010-03-01
Publicado em Journal of Psychiatric Research. Oxford: Pergamon-Elsevier B.V., v. 44, n. 4, p. 224-228, 2010.
ISSN 0022-3956 (Sherpa/Romeo, fator de impacto)
Editor Elsevier B.V.
Extensão 224-228
Fonte http://dx.doi.org/10.1016/j.jpsychires.2009.08.005
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000276008200006
URI http://repositorio.unifesp.br/handle/11600/32336

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