Sutured Clear Corneal Incision: Wound Apposition and Permeability to Bacterial-Sized Particles

Sutured Clear Corneal Incision: Wound Apposition and Permeability to Bacterial-Sized Particles

Autor May, William N. Google Scholar
Castro-Combs, Juan Google Scholar
Kashiwabuchi, Renata T. Google Scholar
Tattiyakul, Woranart Google Scholar
Qureshi-Said, Saima Google Scholar
Hirai, Flavio Autor UNIFESP Google Scholar
Behrens, Ashley Google Scholar
Instituição Univ So Calif
Johns Hopkins Univ
Universidade Federal de São Paulo (UNIFESP)
Resumo Purpose: To determine the effects of single radial or horizontal suture placement in 2-step clear corneal incision (CCI) wound apposition and permeability to particles of India ink.Methods: Five fresh human globes were included. Two 25-gauge needles connected to a saline solution bag and to a digital manometer were inserted through the limbus, 120 degrees apart from each other. Four 2-step CCIs (2.75 mm wide and 3 mm length) were constructed in each cornea. Incisions were divided into 3 groups: single radial suture (SRS), single horizontal suture (SHS), and unsutured group. Optical coherence tomography (OCT) was performed before and after suture placement. With a preset 10 mm Hg intraocular pressure (IOP), India ink was applied to the incision site and a standardized sudden IOP fluctuation was induced. OCT and superficial images were recorded before and after suture placement. India ink inflow and internal and external CCI gapping were outlined and measured by planimeter.Results: the area and linear distance of India ink inflow after pressure challenge in all study groups were higher when compared with pre-pressure measurements; however, this increase was significant in the SRS and SHS groups (P < 0.05). Additionally, SRS placement significantly increased inner wound gapping (P = 0.018), and SHS significantly widened outer wound gape (P = 0.02).Conclusions: Well-constructed unsutured 2-step CCI seems to be more efficient at preventing bacterial-sized particles inflow during sudden changes in IOP, and it seems to offer better wound apposition as assessed by OCT.
Assunto cataract surgery
clear corneal incision
Idioma Inglês
Financiador May Vision Foundation, Los Angeles, California
Research to Prevent Blindness, New York, New York
Johns Hopkins University School of Medicine, Baltimore, Maryland
Research to Prevent Blindness Althouse Special Scholars Award
Fight for Sight, New York, New York
Data 2013-03-01
Publicado em Cornea. Philadelphia: Lippincott Williams & Wilkins, v. 32, n. 3, p. 319-325, 2013.
ISSN 0277-3740 (Sherpa/Romeo, fator de impacto)
Editor Lippincott Williams & Wilkins
Extensão 319-325
Fonte http://dx.doi.org/10.1097/ICO.0b013e31824d0d45
Direito de acesso Acesso restrito
Tipo Artigo
Web of Science WOS:000314818700017
URI http://repositorio.unifesp.br/handle/11600/36052

Mostrar registro completo




Arquivos deste item

Arquivos Tamanho Formato Visualização

Não existem arquivos associados a este item.

Este item aparece na(s) seguinte(s) coleção(s)

Buscar DSpace


Navegar

Minha conta