Convergence of two major pathophysiologic mechanisms in nasal polyposis: immune response to Staphylococcus aureus and airway remodeling

Convergence of two major pathophysiologic mechanisms in nasal polyposis: immune response to Staphylococcus aureus and airway remodeling

Autor Pezato, Rogerio Autor UNIFESP Google Scholar
Balsalobre, Leonardo Autor UNIFESP Google Scholar
Lima, Milena Google Scholar
Bezerra, Thiago F. P. Google Scholar
Voegels, Richard L. Google Scholar
Gregório, Luis Carlos Autor UNIFESP Google Scholar
Stamm, Aldo Cassol Autor UNIFESP Google Scholar
van Zele, Thibaut Google Scholar
Instituição Universidade Federal de São Paulo (UNIFESP)
Univ Ghent
Mil Police Hosp
Universidade de São Paulo (USP)
Resumo This review is addressed two pathophysiologic mechanisms implicated in the pathogenesis of nasal polyposis: the unique remodeling process found in nasal polyp tissue and the immune response of patients with nasal polyposis to Staphylococcus aureus.These two theories converge to the same direction in different aspects, including decreased extracellular matrix production, impaired T regulation and favoring of a Th2 immune response.In patients with nasal polyposis, an exaggerated immune response to Staphylococcus aureus may aggravate the airway remodeling process.
Assunto Airway remodeling
Superantigens
Nasal polyps
Idioma Inglês
Data 2013-03-28
Publicado em Journal of Otolaryngology-head & Neck Surgery. London: Biomed Central Ltd, v. 42, 5 p., 2013.
ISSN 1916-0216 (Sherpa/Romeo, fator de impacto)
Editor Biomed Central Ltd
Extensão 5
Fonte http://dx.doi.org/10.1186/1916-0216-42-27
Direito de acesso Acesso aberto Open Access
Tipo Resenha
Web of Science WOS:000318410000002
URI http://repositorio.unifesp.br/handle/11600/36104

Mostrar registro completo




Arquivos deste item

Nome: WOS000318410000002.pdf
Tamanho: 265.0Kb
Formato: PDF
Descrição:
Visualizar/Abrir

Este item aparece na(s) seguinte(s) coleção(s)

Buscar DSpace


Navegar

Minha conta