Wound healing properties and mucilage content of Pereskia aculeata from different substrates

Wound healing properties and mucilage content of Pereskia aculeata from different substrates

Autor Carvalho, Eber Goulart Google Scholar
Soares, Cristina Pacheco Google Scholar
Blau, Lorena Google Scholar
Menegon, Renato Farina Autor UNIFESP Google Scholar
Joaquim, Walderez Moreira Google Scholar
Instituição Universidade do Vale do Paraíba Instituto de Pesquisa e Desenvolvimento
Universidade Federal de São Paulo (UNIFESP)
Resumo Physiologic growth parameters Wound healing Pereskia aculeata Mill., Cactaceae, is a cactus with high mucilage production, well-known for its nutritional properties. Folk use consists on skin injuries, and mucilage is probably involved in the wound healing activity. This work studied some aspects of its cultivation, specifically regarding soil (substrate), to correlate the effects of nutritional content to mucilage production and to the wound-healing property. Plants were grown under five different soil treatment (sand, crude soil, sand and soil, sand and cattle manure, soil and cattle manure), and after eight months extracts were prepared by turbo-extraction to obtain a crude hydroethanolic extract. We evaluated the effects of these extracts on swelling index, cytotoxicity, and in vitro wound healing property. The results show that the substrate used in cultivation may interfere with mucilage production, but not with cytotoxicity and wound healing, this shows the safety of its use, despite the soil treatment received along the various biomes where P. aculeata is cultivated. Furthermore, morphological studies demonstrated the beneficial effect of the mucilage-containing extract on the fibroblast cell culture, corroborating its folk use for wound healing.
Assunto Cactus cultivation
Physiologic growth parameters
Wound healing
Idioma Inglês
Data 2014-12-01
Publicado em Revista Brasileira de Farmacognosia. Sociedade Brasileira de Farmacognosia, v. 24, n. 6, p. 677-682, 2014.
ISSN 0102-695X (Sherpa/Romeo, fator de impacto)
Editor Sociedade Brasileira de Farmacognosia
Extensão 677-682
Fonte http://dx.doi.org/10.1016/j.bjp.2014.11.008
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000350314800009
SciELO S0102-695X2014000600677 (estatísticas na SciELO)
URI http://repositorio.unifesp.br/handle/11600/8674

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